Following the Rugby World Cup victory against England on Saturday, Scott Williams (knee) and Hallam Amos (shoulder) have sustained injuries that will preclude them from taking any further part in the tournament and they have subsequently been released from the Wales squad.
Both players are currently being assessed by specialists to establish an accurate prognosis.
James Hook and Gareth Anscombe, who were both part of Wales’ Rugby World Cup training squad and featured in warm-up tests ahead of the tournament have been called into the squad as replacements.
Hook will feature in his third RWC squad and will look to add to his tally of 78 International caps. Anscombe, made his International debut against Ireland in August.