Newport Gwent Dragons, who won the tournament last year, will compete against their fellow Welsh Regions on Friday 22nd July at BT Sport Cardiff Arms Park.
The series will continue the following day as Exeter Chiefs host a leg at Sandy Park for the first time in the tournament’s history.
A week later, the 7s will return to Franklin’s Gardens on 29 July with the last group action at Kingston Park on 30 July.
Two teams from each group will qualify for the Singha Premiership Rugby 7s Series Final which will see eight teams competing for the 2016 title at the Ricoh Arena, Coventry on Saturday, 6 August.
“The 7s Series kicked off in 2010 and since then it has become a date to look forward to in the rugby calendar," said the Rugby Director at Premiership Rugby, Phil Winstanley.
“Sevens is at its most high profile this year with its return to the Olympics in Rio and Premiership Rugby continues to lead the way when it comes to club 7s.
“Last year’s final was won with a try in the last second of the final game between Wasps and Newport Gwent Dragons and we can expect this year’s series to be just as exciting.”
Singha Premiership Rugby 7s Schedule
Group A
Date: Friday 22 July
Venue: BT Sport Cardiff Arms Park
Cardiff Blues
Newport Gwent Dragons
Ospreys
Scarlets
Group B
Date: Saturday 23 July
Venue: Sandy Park, Exeter
Bath Rugby
Exeter Chiefs
London Irish/ Promoted Club
Wasps
Group C
Date: Friday 29 July
Venue: Franklin’s Gardens, Northampton Saints
Gloucester Rugby
Harlequins
Northampton Saints
Saracens
Group D
Date: Saturday 30 July
Venue: Kingston Park, Newcastle
Leicester Tigers
Newcastle Falcons
Sale Sharks
Worcester Warriors
Series Final
Date: Saturday 6 August
Venue: Ricoh Arena, Coventry
The top two teams from each group will qualify for the Singha Premiership Rugby 7s Series Final
Tickets for the Singha Premiership Rugby 7s Series are now on sale at premiershiprugby.com/singha7stickets