Wales international Rio Dyer returns to the starting line-up as Dragons RFC travel to Scotland to face Glasgow Warriors in the last 16 of the EPCR Challenge Cup on Saturday evening (kick-off 5.30pm).
Head Coach Dai Flanagan makes a total of nine changes to his side for the European showdown at Scotstoun Stadium.
Dyer makes his club comeback after his Six Nations exploits, while fellow wing Jared Rosser also returns. Centre Max Clark is called into the back line to partner Steff Hughes in midfield.
Jordan Williams moves to full back with Angus O’Brien unavailable as he prepares to welcome his second child with his wife.
A new-look front row sees prop Aki Seiuli pack down against his former club alongside hooker Bradley Roberts and prop Chris Coleman.
Lock Ben Carter joins George Nott in the second row while Aaron Wainwright and Taine Basham return in the back row.
Wales international prop Leon Brown is back among the replacements while there are also call-ups for back row Ben Fry and utility back Ioan Davies.
"Glasgow were very impressive and did some stuff that no-one does to Munster away last weekend," said Flanagan.
"They play a great brand of rugby and it's an opportunity to test ourselves against one of the best in the league.
"It's a big challenge but one we're looking forward to. We're excited to get back out there and show that what was on the field last weekend (against Ospreys) wasn't us.”
Dragons RFC: Jordan Williams, Rio Dyer, Steff Hughes, Max Clark, Jared Rosser, Will Reed, Rhodri Williams (capt); Aki Seiuli, Bradley Roberts, Chris Coleman, Ben Carter, George Nott, Ross Moriarty, Taine Basham, Aaron Wainwright
Replacements: Elliot Dee, Rhodri Jones, Leon Brown, Huw Taylor, Sean Lonsdale, Ben Fry, Lewis Jones, Ioan Davies
Unavailable: Gonzalo Bertranou (foot), Joe Davies (knock), Sam Davies (hip), Jack Dixon (foot), JJ Hanrahan (hip), Ashton Hewitt (tricep), Ollie Griffiths (pectoral), Harri Keddie (knock), Angus O’Brien (paternity), Aneurin Owen (knee), David Richards (hamstring), Will Rowlands (shoulder), Matthew Screech (suspension), Sio Tomkinson (suspension)