Dragons RFC quartet Aaron Wainwright, Rio Dyer, Elliot Dee and Taine Basham all featured as Wales completed a clean sweep of World Cup pool matches with a bonus-point 43-19 victory over Georgia.
Louis Rees-Zammit scored a hat-trick as Warren Gatland's side topped Pool C to set up a likely quarter-final meeting with Argentina or Japan.
Tomas Francis, Liam Williams and George North also crossed for Wales. Georgia threatened a second-half comeback after tries from Merab Sharikadze, Vano Karkadze and Davit Niniashvili.
Wales will learn their last-eight fate on Sunday, when Argentina take on Japan in a virtual quarter-final play-off, also at Nantes' Stade de Beaujoire.
