A 21 point burst in the space of four first half minutes set impressive Munster on course for victory at Dragons.
Diarmuid Kilgallen crossed early before a blitz of scores from Alex Kendellen, Ben O'Connor and a penalty try. Prop Dian Bleuler barged over to give Munster a 31-0 half-time lead.
Chris Coleman, Harry Wilson and Dane Blacker all scored second-half tries as Dragons went close to a bonus point.
