Toby Faletau has been selected at No.8 for Wales for their RBS 6 Nations opener against Ireland in Dublin.
Danny Lydiate lost his fitness battle for selection in the back row and will be replaced by Osprey Ryan Jones.
Scarlets fly half Priestland and Blues centre Roberts have recovered from knee injuries in time to take their places in a starting line-up which shows six changes to that which faced Australia at the Millennium Stadium in December and just five from that which defeated Ireland in the Rugby World Cup quarter-finals.
"We have been able to retain continuity in some key areas, we have been working hard and we feel we are approaching this match with the right attitude and with some good preparation work done," said Wales head coach Warren Gatland.
"We are two sides who know each other well, Ireland will not have enjoyed losing to us in New Zealand, they will want to redress the balance in Dublin this weekend, but they will find us in just as determined mood."
WALES: Leigh Halfpenny; Alex Cuthbert, Jonathan Davies, Jamie Roberts, George North; Rhys Priestland, Michael Phillips; Rhys Gill, Huw Bennett, Adam Jones, Bradley Davies, Ian Evans, Ryan Jones, Sam Warburton (C), Toby Faletau.
Replacements: Ken Owens, Paul James, Andy Powell, Justin Tipuric, Lloyd Williams, James Hook, Scott Williams
