The Men of Gwent travel to the RDS Arena with high hopes having done the double over Leinster last season.
The South African skipper will lead the Men of Gwent out after two weeks of training and preparations have taken place since their win against Zebre at Rodney Parade in Round 2 of the Guinness PRO12.
Looking back at last years win against Leinster, Landman commented: "Nick Crosswell got a yellow card in the first few minutes and I thought 'oh no, we can't play with 14 men against them'!
"But we turned things around, our kicking game was great, we left nothing on the pitch, got the 'W'.
"They won't underestimate us this time but I think that was the same when they came to Rodney Parade with an even better side than in Dublin and we won again (25-22).
"We know it will be a tough game and they will have a strong side even though they are affected by World Cup call-ups. They've got depth and a big budget but last season gives us confidence."
Full back Carl Meyer joins wings Ashton Hewitt and Tom Prydie in the back three. The centre pairing sees Ross Wardle and Adam Warren retain their positions. Fly-half Jason Tovey also keeps his place as well as Sarel Pretorius as scrum-half.
The front row has one change made to it as hooker Hugh Gustafson joins props Boris Stankovich and Brok Harris. The second row also has one change made to it as Nick Crosswell joins skipper Rynard Landman. The back row has two changes made to it as James Thomas and James Benjamin join number 8 Ed Jackson.
The replacements bench sees six changes made to it as Elliot Dee, Matthew Screech, Nic Cudd, Luc Jones, Angus O’Brien and Aled Brew join Phil Price and Shaun Knight.
Dragons team to face Leinster
Carl Meyer, Ashton Hewitt, Ross Wardle, Adam Warren, Tom Prydie, Jason Tovey, Sarel Pretorius; Boris Stankovich, Hugh Gustafson, Brok Harris, Nick Crosswell, Rynard Landman ©, James Thomas, James Benjamin, Ed Jackson.
Replacements: Elliot Dee, Phil Price, Shaun Knight, Matthew Screech, Nic Cudd, Luc Jones, Angus O’Brien, Aled Brew.